(And when We cause mankind) the disbelievers of Mecca (to taste of mercy) bounty (they rejoice therein) without giving thanks for it; (but if an evil thing) hardship, tightness, drought or sickness (befall them as the consequence of their own deeds) which they did in their state of idolatry, (lo! they are in despair) they despair from the mercy of Allah, and fail to withstand it!